The 14th puzzle, entitled "Bloodlines", isn't really that hard in Assassin's Creed 2. Set 1: Highlight the images that depict women and gods in amorous entanglements (especially if those gods are disguised as animals). For more info, watch the whole gameplay.
This is an Assassin's Creed II walkthrough for Glyph Puzzle #14. The Glyph Puzzles can actually be some of the hardest challenges the game will throw your way. Keep in mind that the puzzles will be made available to you in the same order, regardless of which Glyphs you find first.
Mahalo's Assassins Creed 2 Walkthroughs are more than enough information for you to play the game yourself, and they teach you everything your need to be prepared for when playing yourself. This video walkthrough focuses on Glyph Puzzle 14.
Assassin's Creed 2 by Ubisoft is the action-adventure video game playable on PlayStation 3, Xbox 360, Sony PSP, and Nintendo DS video game consoles, along with Microsoft Windows. It is the direct sequel of Assassin's Creed and revolves around Ezio, and is set in Renaissance Italy. Ezio befriends Leonardo da Vinci, who provides experimental weapons and gadgets, and takes on Florence's most powerful families and ventures throughout the canals of Venice, where he learns to become a master assassin. The Assassin's Creed 2 gameplay is a mixture of action, stealth, and acrobatics.