Play Along: At the start of the mission, you simply need to follow the leader through the city. Do your best not to bump into anyone, as Ezio will drop the chest if you do. Eventually, you read the end of the trail and a cut scene takes over.
Now the mission gets serious. You've got to defeat Rodrigo Borgia, a feat easier said than done. In the first stage of the fight, you're best off using a sword and aggressively throwing strikes at Rodrigo. He'll naturally block most everything, and you can't get a quick kill, but you'll whittle away at his health, slowly but surely. Be ready to counter his attacks when he throws them, but if you're aggressive enough you can back Rodrigo into a corner and he won't be able to do much. For more info, watch the whole gameplay.
This is an Assassin's Creed II walkthrough for Mission 66: Play Along.
Mahalo's Assassins Creed 2 Walkthroughs are more than enough information for you to play the game yourself, and they teach you everything your need to be prepared for when playing yourself. This video walkthrough focuses on Mission 66: Play Along.
Assassin's Creed 2 by Ubisoft is the action-adventure video game playable on PlayStation 3, Xbox 360, Sony PSP, and Nintendo DS video game consoles, along with Microsoft Windows. It is the direct sequel of Assassin's Creed and revolves around Ezio, and is set in Renaissance Italy. Ezio befriends Leonardo da Vinci, who provides experimental weapons and gadgets, and takes on Florence's most powerful families and ventures throughout the canals of Venice, where he learns to become a master assassin. The Assassin's Creed 2 gameplay is a mixture of action, stealth, and acrobatics.